Endocrine Abstracts

Introduction: Pituitary apoplexy (PA) is a rare endocrine emergency with less described entity being its subacute/non-acute presentation. Incidence of PA is difficult to determine, varying 2%-12% of pituitary adenoma. Hypopituitarism in PA is observed in up to 70% of cases with diabetes Insipidus (DI) observed in <5% of cases and mostly transient.Case description: 82-year old female with pituitary macroprolactinoma (1.5 cm) presented with 3-week hist...

Primary hyperparathyroidism (PHPT) is one of the common endocrine conditions and is frequently associated with hypertension and increased cardiovascular mortality but this association is not well recognised. The purpose of this study was to evaluate the effect of parathyroidectomy on blood pressure. The data of 112 patients who attended our out patients clinic over the period of 12 months, with the confirmed diagnosis of primary hyperparathyroidism was evaluated. Average age w...

Background: Patient Safety Noticed issued by Welsh Government in June 2021 set out multiple action plans to be implemented by Welsh health boards to improve recognition and management of adrenal crisis. Hospitals were advised to review policies to ensure all patients at risk of Adrenal Crisis [(primary/secondary/tertiary adrenal insufficiency (AI)] were identified.Aim: In response, our hospital commenced a quality improv...

Background: Cushing’s syndrome is rare (1.8-3.2 cases/million population)1, with Cushing’s disease (CD) accounting >70%. We seek to highlight a rare complication, spinal epidural lipomatosis (SEL), rare cause of spinal compression (prevalence-2.5%2), commonly related to exogenous steroid use with 3 reported cases secondary to CD3,4,5.Case: 36-years old man, background asthma and alcohol excess presented wit...

Background: Carbimazole is a commonly used and effective treatment for hyperthyroidism. Although on the World Health Organisation’s list of essential medicines, it comes with the potentially significant side effect of agranulocytosis. We set out a Quality Improvement Project to improve communication with patients to ensure their understanding through creating a patient information leaflet.Methods: 30 patients receiv...

We report the case of a previously healthy, 40 years old obese male, who was admitted in emergency with complaints of chest pain, shortness of breath and loose stools. His physical examination was relatively unremarkable except for sinus tachycardia and restlessness. He had no history of ischemic heart disease. He was admitted under cardiologists and had various investigations (echocardiogram, stress test and coronary angiogram), all normal. Due to the presentation, thyroid fu...

Aim: To assess side effects of testosterone (TRT).Introduction: TRT in men with hypogonadism helps improve libido, erectile dysfunction, energy levels and bone density. However the risks/benefits of TRT in terms of ischemic heart disease (IHD), stroke and venous thromboembolism (VTE) is controversial no definitive answers from current evidence. We evaluated the side effects of TRT in patients attending endocrinology outpatient clinic between 2009 to 2019...

Aim: To compare efficacy of different formulations of TRT in treatment of hypogonadismBackground: Different formulations of testosterone are available for treatment of hypogonadism in men. TRT improves libido, sexual function, bone density and general well-being. We analysed data of 106 patients on TRT to compare efficacy of topical and injectable formulations.Methods: It’s a retrospective data analysis of 106 patient receivin...

Introduction: With the increased use of imaging modalities, detection of Adrenal Incidentaloma (AI) has become common.Aim: We evaluated management of patients with AI to improve service delivery.Method: Patients with AI referred to our endocrinology outpatient service (2006–2019). Data was collected from electronic case records and radiology reporting system. Demography, biochemical investigations, time interval between two sc...